3-Chlorokenpaullone

Molbank

Oliver C. F. Orban¹  Ricarda S. Korn¹  Lisa Unger¹  Akim Yildiz¹ 

[1] Institut für Medizinische und Pharmazeutische Chemie, Technische Universität Braunschweig, Beethovenstr. 55, 38106 Braunschweig, Germany

关键词: kenpaullone;    paullone;    protein kinase inhibitor;    Fischer indole synthesis;   

DOI  :  10.3390/M856

来源: mdpi

【 摘 要 】

3-Chlorokenpaullone (9-bromo-3-chloro-7,12-dihydroindolo[3,2-d][1]benz­azepin-6(5H)-one) is a novel derivative of the protein kinase inhibitor kenpaullone. The title compound was synthesized by a Fischer indole reaction from 8-chloro-3,4-dihydro-1H-1-benzazepin-2,5-dione and 4-bromophenylhydrazine. It was characterized for structural identity by elemental analysis and spectroscopic methods (IR, NMR, EI-MS) and checked for purity by HPLC.

【 授权许可】

CC BY   
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.