期刊论文详细信息
Green Chemistry Letters and Reviews
Novel biodegradable protonic ionic liquid for the Fischer indole synthesis reaction
William C. Neuhaus1 
关键词: Ionic liquids;    indole;    Fischer indole synthesis;    tetramethylguanidinium;    biodegradable;   
DOI  :  10.1080/17518253.2016.1149231
学科分类:化学(综合)
来源: Taylor & Francis
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【 摘 要 】

Novel eco-friendly tetramethylguanidinium propanesulfonic acid trifluoromethylacetate ([TMGHPS][TFA]) ionic liquid was developed as catalyst and medium for the Fischer indole synthesis of a wide variety of hydrazines and ketones. The indole products were isolated in high yields and with minimal amounts of organic solvent. This reaction showed that [TMGHPS][TFA] can be regenerated and reused with reproducible yields without eroding the integrity of the ionic liquid.

【 授权许可】

Unknown   

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