Chemical Reactions Directed Peptide Self-Assembly

International Journal of Molecular Sciences

Dnyaneshwar B. Rasale²  Apurba K. Das¹ 

[1] Department of Chemistry, Indian Institute of Technology Indore, Khandwa Road, Indore 452017, India; E-Mail

关键词: chemical reaction;    peptide;    self-assembly;    enzyme;    native chemical ligation;   

DOI  :  10.3390/ijms160510797

来源: mdpi

【 摘 要 】

Fabrication of self-assembled nanostructures is one of the important aspects in nanoscience and nanotechnology. The study of self-assembled soft materials remains an area of interest due to their potential applications in biomedicine. The versatile properties of soft materials can be tuned using a bottom up approach of small molecules. Peptide based self-assembly has significant impact in biology because of its unique features such as biocompatibility, straight peptide chain and the presence of different side chain functionality. These unique features explore peptides in various self-assembly process. In this review, we briefly introduce chemical reaction-mediated peptide self-assembly. Herein, we have emphasised enzymes, native chemical ligation and photochemical reactions in the exploration of peptide self-assembly.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.