Endiandric Acid Derivatives and Other Constituents of Plants from the Genera Beilschmiedia and Endiandra (Lauraceae)

Biomolecules

Bruno Ndjakou Lenta³  Jean Rodolphe Chouna¹  Pepin Alango Nkeng-Efouet¹  Norbert Sewald² 

[1] Department of Chemistry, University of Dschang, P.O. Box 67, Dschang, Cameroon; E-Mails:;Organic and Bioorganic Chemistry, Chemistry Department, Bielefeld University, P.O. Box 100131, 33501 Bielefeld, Germany; E-Mail:;Department of Chemistry, Higher Teacher Training College, University of Yaoundé 1, P.O. Box 47, Yaoundé, Cameroon

关键词: Lauraceae;    Beilschmiedia;    Endiandra;    chemical constituents;    endiandric acid;    alkaloids;    biological activities;   

DOI  :  10.3390/biom5020910

来源: mdpi

【 摘 要 】

Plants of the Lauraceae family are widely used in traditional medicine and are sources of various classes of secondary metabolites. Two genera of this family, Beilschmiedia and Endiandra, have been the subject of numerous investigations over the past decades because of their application in traditional medicine. They are the only source of bioactive endiandric acid derivatives. Noteworthy is that their biosynthesis contains two consecutive non-enzymatic electrocyclic reactions. Several interesting biological activities for this specific class of secondary metabolites and other constituents of the two genera have been reported, including antimicrobial, enzymes inhibitory and cytotoxic properties. This review compiles information on the structures of the compounds described between January 1960 and March 2015, their biological activities and information on endiandric acid biosynthesis, with 104 references being cited.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.