Chemical Constituents of the Root of Jasminum giraldii

Molecules

Zhenggang Yue³  Hui Qin¹  Yuhua Li³  Yang Sun³  Zhipeng Wang³  Tiehong Yang³  Li Liu³  Minchang Wang²  Feng Feng¹ 

[1] Department of Natural Medicinal Chemistry, China Pharmaceutical University, Nanjing 210009, Jiangsu, China;Xi’an Modern Chemistry Research Institute, Xi’an 710032, Shaanxi, China;Department of Pharmacology, School of Pharmacy, the Fourth Military Medical University, Xi’an 710032, Shaanxi, China

关键词: Jasminum giraldii;    oleaceae;    chemical constituents;    cytotoxic activity;   

DOI  :  10.3390/molecules18044766

来源: mdpi

【 摘 要 】

abstract: Two new compounds, ethylconiferin (1) and (−)-lariciresinol 4-(6'''-O-cinnamyl-β-D-glucopyranoside) (2), along with the three known compounds (+)-pinoresinol (3), (+)-cycloolivil (4), nobiletin (5), were isolated from the root of Jasminum girialdii. All these compounds were isolated for the first time from this source. Their structures were elucidated on the basis of extensive spectroscopic analysis and chemical methods. In addition, the in vitro cytotoxic activity of these compounds was evaluated. The results showed that none of the compounds had any significant inhibitory activities on the proliferation of HCT-116 and SW-620 cells.

【 授权许可】

CC BY   
© 2013 by the authors; licensee MDPI, Basel, Switzerland.