Molecules | |
Synthesis and Biological Evaluation of Hydrazone Derivatives as Antifungal Agents | |
Bruna B. Casanova3  Mauro N. Muniz3  Thayse de Oliveira2  Luís Flavio de Oliveira1  Michel M. Machado1  Alexandre M. Fuentefria2  Grace Gosmann3  Simone C. B. Gnoatto3  | |
[1] Departamento de Farmácia, Universidade Federal do Pampa, Km 592, Uruguaiana 97500-970, RS, Brazil; E-Mails:;Laboratório de Micologia Aplicada, Departamento de Analises, Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90610-000, RS, Brazil; E-Mails:;Laboratório de Fitoquímica e Síntese Orgânica (LAFIS), Faculdade de Farmácia, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre 90610-000, RS, Brazil; E-Mails: | |
关键词: aldehydes; hydrazones; emerging yeasts; antifungal activity; | |
DOI : 10.3390/molecules20059229 | |
来源: mdpi | |
【 摘 要 】
Emerging yeasts are among the most prevalent causes of systemic infections with high mortality rates and there is an urgent need to develop specific, effective and non-toxic antifungal agents to respond to this issue. In this study 35 aldehydes, hydrazones and hydrazines were obtained and their antifungal activity was evaluated against
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190012252ZK.pdf | 1030KB | download |