Green Polymer Chemistry: Enzyme Catalysis for Polymer Functionalization

Molecules

Sanghamitra Sen²  Judit E. Puskas¹ 

[1] Department of Chemical and Biomolecular Engineering, The University of Akron, Akron, OH 44325, USA; E-Mail

关键词: enzyme catalysis;    Candida antarctica lipase B;    transesterification;    Michael addition;    polymer functionalization;    poly(ethylene glycol);    polyisobutylene;    polysiloxanes;    polystyrene;    regioselectivity;    chemoselectivity;   

DOI  :  10.3390/molecules20059358

来源: mdpi

【 摘 要 】

Enzyme catalyzed reactions are green alternative approaches to functionalize polymers compared to conventional methods. This technique is especially advantageous due to the high selectivity, high efficiency, milder reaction conditions, and recyclability of enzymes. Selected reactions can be conducted under solventless conditions without the application of metal catalysts. Hence this process is becoming more recognized in the arena of biomedical applications, as the toxicity created by solvents and metal catalyst residues can be completely avoided. In this review we will discuss fundamental aspects of chemical reactions biocatalyzed by Candida antarctica lipase B, and their application to create new functionalized polymers, including the regio- and chemoselectivity of the reactions.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.