Molecules | |
Molecular Interactions of β-(1→3)-Glucans with Their Receptors | |
Laurent Legentil1  Franck Paris1  Caroline Ballet1  Sophie Trouvelot4  Xavier Daire4  Vaclav Vetvicka3  Vincent Ferrières1  Els Van Damme2  | |
[1] Ecole Nationale Supérieure de Chimie de Rennes, CNRS, UMR 6226, 11 Allée de Beaulieu, CS 50837, 35708 Rennes Cedex 7, France; E-Mails:Ecole Nationale Supérieure de Chimie de Rennes, CNRS, UMR 6226, 11 Allée de Beaulieu, CS 50837, 35708 Rennes Cedex 7, France;;Department of Pathology, University of Louisville, Louisville, KY 40202, USA;INRA, UMR AgroSup/INRA/uB 1347 Agroécologie, Pôle Interactions Plantes-Microorganismes-ERL CNRS 6300, 21065 Dijon Cedex, France; E-Mails: | |
关键词: β-(1→3)-glucans; Dectin-1; CR3; glycolipids; langerin; CBM; | |
DOI : 10.3390/molecules20069745 | |
来源: mdpi | |
【 摘 要 】
β-(1→3)-Glucans can be found as structural polysaccharides in cereals, in algae or as exo-polysaccharides secreted on the surfaces of mushrooms or fungi. Research has now established that β-(1→3)-glucans can trigger different immune responses and act as efficient immunostimulating agents. They constitute prevalent sources of carbons for microorganisms after subsequent recognition by digesting enzymes. Nevertheless, mechanisms associated with both roles are not yet clearly understood. This review focuses on the variety of elucidated molecular interactions that involve these natural or synthetic polysaccharides and their receptors,
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190012007ZK.pdf | 1538KB | download |