Multidisciplinary Approach to Determine the Optimal Time and Period for Extracting the Essential Oil from Mentha suaveolens Ehrh †

Molecules

Stefania Garzoli²  Adele Pirolli³  Elisabetta Vavala⁴  Antonella Di Sotto¹  Gianni Sartorelli³  Mijat Božović³  Letizia Angiolella⁴  Gabriela Mazzanti¹  Federico Pepi²  Rino Ragno³ 

[1] Department of Physiology and Pharmacology “Vittorio Erspamer”, “Sapienza” University, P.le Aldo Moro 5, 00185 Rome, Italy; E-Mails:;Department of Drug Chemistry and Technology, “Sapienza” University, P.le Aldo Moro 5, 00185 Rome, Italy; E-Mails:;Rome Center for Molecular Design, Department of Drug Chemistry and Technology, “Sapienza” University, P.le Aldo Moro 5, 00185 Rome, Italy; E-Mails:;Department of Public Health and Infectious Diseases, “Sapienza” University, P.le Aldo Moro 5, 00185 Rome, Italy; E-Mails:

关键词: Mentha suaveolens;    GC/MS;    essential oils;    piperitenone oxide;   

DOI  :  10.3390/molecules20069640

来源: mdpi

【 摘 要 】

A comprehensive study on essential oils (EOs) extracted from some Mentha suaveolens L. samples, collected in the countryside of Tarquinia, is reported. In this study, the procedure for essential oil preparation, in terms of harvesting and extraction time, was analyzed in detail for the first time. The GC/MS analysis, carried out on 18 samples, revealed that piperitenone oxide (PO), the main essential oils’ chemical constituent, is primarily responsible for the related antifungal activity. Nevertheless, EOs with lower PO content indicate that other chemicals, such as para-cymenene, may participate in exerting the EOs’ antifungal effect. Furthermore, the bacterial reverse mutation assay highlighted lack of mutagenic effect in all tested samples. Analysis of the results indicated that for higher activity, the essential oils should be produced with 3 h maximum hydrodistillation, regardless of the harvesting time. Differently, the maximum essential oil yield can be obtained in August and the highest piperitenone oxide percentage is obtainable in July.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.