Carbamazepine Positives Due To 10,11-Dihydro-10-Hydroxycarbamazepine Breakdown in the GC/MS Injector Port

Johnson RD, Lewis RJ, Angier MK

FAA Office of Aerospace Medicine - Civil Aerospace Medical Institute

关键词: Forensic Toxicology;    Oxcarbazepine;    Carbamazepine;    GC/MS;    LC/MS;    Aircraft Accident Investigation;   

RP-ID  :  DOT/FAA/AM-10/4

美国|英语

来源: Federal Aviation Administration

【 摘 要 】

During the investigation of aviation accidents, postmortem specimens from accident victims are submitted to the Federal Aviation Administration's Civil Aerospace Medical Institute (CAMI) for toxicological analysis. A case recently received by CAMI screened positive for the anticonvulsant medication carbamazepine (Tegretol) by gas chromatography/mass spectrometry (GC/MS).