Design and Evaluation of Potentiometric Principles for Bladder Volume Monitoring: A Preliminary Study

Sensors

Shih-Ching Chen¹  Tsung-Hsun Hsieh²  Wen-Jia Fan¹  Chien-Hung Lai¹  Chun-Lung Chen¹  Wei-Feng Wei³  Chih-Wei Peng¹ 

[1] Department of Physical Medicine and Rehabilitation, School of Medicine, College of Medicine, Taipei Medical University, No. 250, Wuxing Street, Taipei 11031, Taiwan; E-Mails:;Graduate Institute of Neural Regenerative Medicine, Taipei Medical University, No. 250, Wuxing Street, Taipei 11031, Taiwan; E-Mail:;Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, No.1, Roosevelt Road, Sec.4, Taipei 10617, Taiwan; E-Mail:

关键词: potentiometer;    real time;    pig bladder;    implantable;    sensor;   

DOI  :  10.3390/s150612802

来源: mdpi

【 摘 要 】

Recent advances in microelectronics and wireless transmission technology have led to the development of various implantable sensors for real-time monitoring of bladder conditions. Although various sensing approaches for monitoring bladder conditions were reported, most such sensors have remained at the laboratory stage due to the existence of vital drawbacks. In the present study, we explored a new concept for monitoring the bladder capacity on the basis of potentiometric principles. A prototype of a potentiometer module was designed and fabricated and integrated with a commercial wireless transmission module and power unit. A series of in vitro pig bladder experiments was conducted to determine the best design parameters for implementing the prototype potentiometric device and to prove its feasibility. We successfully implemented the potentiometric module in a pig bladder model in vitro, and the error of the accuracy of bladder volume detection was <±3%. Although the proposed potentiometric device was built using a commercial wireless module, the design principles and animal experience gathered from this research can serve as a basis for developing new implantable bladder sensors in the future.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.