Marine Drugs | |
Can Some Marine-Derived Fungal Metabolites Become Actual Anticancer Agents? | |
Nelson G. M. Gomes1  Florence Lefranc3  Anake Kijjoa1  Robert Kiss2  | |
[1] ICBAS—Instituto de Ciências Biomédicas Abel Salazar, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal; E-Mails:;Laboratoire de Cancérologie et de Toxicologie Expérimentale, Faculté de Pharmacie, Université Libre de Bruxelles, Campus de la Plaine, CP205/1, Boulevard du Triomphe, 1050 Brussels, Belgium;Service de Neurochirurgie, Hôpital Erasme, Université Libre de Bruxelles, 808 Route de Lennik, 1070 Brussels, Belgium; E-Mail: | |
关键词:
marine fungi;
natural products;
anticancer;
chemotherapeutic;
cytotoxic;
multidrug resistance;
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DOI : 10.3390/md13063950 | |
来源: mdpi | |
【 摘 要 】
Marine fungi are known to produce structurally unique secondary metabolites, and more than 1000 marine fungal-derived metabolites have already been reported. Despite the absence of marine fungal-derived metabolites in the current clinical pipeline, dozens of them have been classified as potential chemotherapy candidates because of their anticancer activity. Over the last decade, several comprehensive reviews have covered the potential anticancer activity of marine fungal-derived metabolites. However, these reviews consider the term “
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
Files | Size | Format | View |
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RO202003190010857ZK.pdf | 457KB | download |