Investigation of Marine-Derived Fungal Diversity and Their Exploitable Biological Activities

Marine Drugs

Joo-Hyun Hong²  Seokyoon Jang²  Young Mok Heo²  Mihee Min²  Hwanhwi Lee²  Young Min Lee²  Hanbyul Lee²  Jae-Jin Kim¹ 

[1] Division of Environmental Science & Ecological Engineering, College of Life Sciences & Biotechnology, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 136-713, Korea;

关键词: antioxidant activity;    biological control;    cellulolytic enzyme activity;    marine fungi;    phylogenetic analysis;   

DOI  :  10.3390/md13074137

来源: mdpi

【 摘 要 】

Marine fungi are potential producers of bioactive compounds that may have pharmacological and medicinal applications. Fungi were cultured from marine brown algae and identified using multiple target genes to confirm phylogenetic placement. These target genes included the internal transcribed spacer (ITS), the nuclear large subunit (LSU), and the β-tubulin region. Various biological activities of marine-derived fungi were evaluated, including their antifungal, antioxidant and cellulolytic enzyme activities. As a result, a total of 50 fungi was isolated from the brown algae Sargassum sp. Among the 50 isolated fungi, Corollospora angusta was the dominant species in this study. The genus Arthrinium showed a relatively strong antifungal activity to all of the target plant pathogenic fungi. In particular, Arthrinium saccharicola KUC21221 showed high radical scavenging activity and the highest activities in terms of filter paper units (0.39 U/mL), endoglucanase activity (0.38 U/mL), and β-glucosidase activity (1.04 U/mL).

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.