All Silicon Micro-GC Column Temperature Programming Using Axial Heating

Micromachines

Milad Navaei²  Alireza Mahdavifar²  Jean-Marie D. Dimandja³  Gary McMurray¹  Peter J. Hesketh² 

[1] Food Processing Center, Georgia Tech Research Institute (GTRI), Atlanta, GA 30318, USA; E-Mail:;School of Mechanical Engineering, Georgia Institute of Technology, Atlanta, GA 30324, USA; E-Mails:;Department of Chemistry, Spelman College, Atlanta, GA 30314, USA; E-Mail:

关键词: gas chromatography;    MEMS;    joule heating;    thermal gradient;   

DOI  :  10.3390/mi6070865

来源: mdpi

【 摘 要 】

In this work we present a high performance micro gas chromatograph column with a novel two dimensional axial heating technique for faster and more precise temperature programming, resulting in an improved separation performance. Three different axial resistive heater designs were simulated theoretically on a 3.0 m × 300 μm × 50 μm column for the highest temperature gradient on a 22 by 22 μm column. The best design was then micro-fabricated and evaluated experimentally. The simulation results showed that simultaneous temperature gradients in time and distance along the column are possible by geometric optimization of the heater when using forced convection. The gradients along the column continuously refocused eluting bands, offsetting part of the chromatographic band spreading. The utility of this method was further investigated for a test mixture of three hydrocarbons (hexane, octane, and decane).

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.