Nutrients | |
Alcohol and Difficulty Conceiving in the SUN Cohort: A Nested Case-Control Study | |
Cristina Lopez-del Burgo2  Alfredo Gea2  Jokin de Irala2  Miguel A. Martínez-González2  JorgeE. Chavarro1  | |
[1] Department of Epidemiology, Harvard T. H. Chan School of Public Health, 02115 Boston, MA, USA; E-Mail:;Department of Preventive Medicine and Public Health, School of Medicine, University of Navarra, 31008 Pamplona, Navarra, Spain; E-Mails: | |
关键词: fertility; nested case-control study; diet; alcohol; wine; beer; | |
DOI : 10.3390/nu7085278 | |
来源: mdpi | |
【 摘 要 】
The role of alcohol on fertility remains unclear. We aimed to investigate the association between alcohol and specific alcoholic beverages consumption and the risk of difficulty getting pregnant. We used a case-control study nested within the Seguimiento Universidad de Navarra (SUN) cohort, a prospective, dynamic and multipurpose cohort of 21,705 Spanish university graduates, followed biennially with mailed questionnaires. We identified 686 case-control pairs, matched for age and time in the cohort. Cases were women reporting difficulty getting pregnant. Controls did not consult due to difficulty conceiving and had at least one child during follow-up. After adjustment for potential confounders, we found no association between self-reported difficulty getting pregnant and the number of alcoholic beverages consumed per week, (Odds Ratio [OR] > 5 drinks/week
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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RO202003190009106ZK.pdf | 272KB | download |