Aptamer-Based Screens of Human Body Fluids for Biomarkers

Microarrays

Dania Albaba²  Sanam Soomro²  Chandra Mohan¹ 

[1] Department of Biomedical Engineering, University of Houston, 3605 Cullen Blvd, Houston, TX 77204, USA;

关键词: biomarker;    aptamer;    diagnostics;    immunoassay;    microarray;   

DOI  :  10.3390/microarrays4030424

来源: mdpi

【 摘 要 】

In recent years, aptamers have come to replace antibodies in high throughput multiplexed experiments. The aptamer-based biomarker screening technology, which kicked off in 2010, is capable of interrogating thousands of proteins in a very small sample volume. With this new technology, researchers hope to find clinically appropriate biomarkers for a myriad of illnesses by screening human body fluids. In this work, we have reviewed a total of eight studies utilizing aptamer-based biomarker screens of human body fluids, and have highlighted novel protein biomarkers discovered.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.