Molecules | |
Design and Synthesis of New 2-Aryl-4,5-dihydro-thiazole Analogues: |
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Fangfang Tan2  Baojun Shi1  Jian Li2  Wenjun Wu1  Jiwen Zhang2  | |
[1] Institute of Pesticide Science, Northwest Agriculture and Forestry University, Yangling 712100, China;College of Science, Northwest Agriculture and Forestry University, Yangling 712100, China; | |
关键词: synthesis; 4; 5-dihydrothiazole; antibacterial activity; antibacterial mechanism; | |
DOI : 10.3390/molecules201119680 | |
来源: mdpi | |
【 摘 要 】
Sixty 2-aryl-4,5-dihydrothiazoles were designed and synthesized in yields ranging from 64% to 89% from cysteine and substituted-benzonitriles via a novel metal- and catalyst-free method. The structures of the title compounds were confirmed mainly by NMR spectral data analysis. Antibacterial activity assays showed that the compounds (
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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