Vitamin D and Reproduction: From Gametes to Childhood

Healthcare

Krista D. Sowell¹  Carl L. Keen¹  Janet Y. Uriu-Adams¹ 

[1] Department of Nutrition, University of California, Davis, One Shields Avenue, Davis, CA 95616, USA; E-Mails:

关键词: vitamin D;    vitamin D supplementation;    pregnancy;    fertility;    toxicity;    preeclampsia;    gestational diabetes;    allergic disease;   

DOI  :  10.3390/healthcare3041097

来源: mdpi

【 摘 要 】

Vitamin D is well recognized for its essentiality in maintaining skeletal health. Recent research has suggested that vitamin D may exert a broad range of roles throughout the human life cycle starting from reproduction to adult chronic disease risk. Rates of vitamin D deficiency during pregnancy remain high worldwide. Vitamin D deficiency has been associated with an increased risk of fertility problems, preeclampsia, gestational diabetes, and allergic disease in the offspring. Vitamin D is found naturally in only a few foods thus supplementation can provide an accessible and effective way to raise vitamin D status when dietary intakes and sunlight exposure are low. However, the possibility of overconsumption and possible adverse effects is under debate. The effect of vitamin D supplementation during pregnancy and early life on maternal and infant outcomes will be of particular focus in this review.

【 授权许可】

CC BY   
© 2015 by the authors; licensee MDPI, Basel, Switzerland.