International Journal of Molecular Sciences | |
The Autonomous Glycosylation of Large DNA Viruses | |
Francesco Piacente2  Matteo Gaglianone2  Maria Elena Laugieri2  Michela G. Tonetti1  | |
[1] Department of Experimental Medicine and Center of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV, 1, 16132 Genova, Italy | |
关键词:
NCLDV;
chloroviruses;
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DOI : 10.3390/ijms161226169 | |
来源: mdpi | |
【 摘 要 】
Glycosylation of surface molecules is a key feature of several eukaryotic viruses, which use the host endoplasmic reticulum/Golgi apparatus to add carbohydrates to their nascent glycoproteins. In recent years, a newly discovered group of eukaryotic viruses, belonging to the Nucleo-Cytoplasmic Large DNA Virus (NCLDV) group, was shown to have several features that are typical of cellular organisms, including the presence of components of the glycosylation machinery. Starting from initial observations with the chlorovirus PBCV-1, enzymes for glycan biosynthesis have been later identified in other viruses; in particular in members of the
【 授权许可】
CC BY
© 2015 by the authors; licensee MDPI, Basel, Switzerland.
【 预 览 】
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