Is Stevia rebaudiana Bertoni a Non Cariogenic Sweetener? A Review

Molecules

Gianmaria Fabrizio Ferrazzano³  Tiziana Cantile³  Brunella Alcidi³  Marco Coda³  Aniello Ingenito³  Armando Zarrelli²  Giovanni Di Fabio²  Antonino Pollio⁴  Jean Jacques Vanden Eynde¹ 

[1] Department of Neuroscience, Reproductive and Oral Sciences, Section of Paediatric Dentistry, University of Naples, Federico II, Naples 80131, ItalyDepartment of Chemical Sciences, Complesso Universitario di Monte Sant’Angelo, Cupa Nuova Cintia, 21-80126-Napoli, University of Naples, Federico II, Naples 80126, Italy;Department of Neuroscience, Reproductive and Oral Sciences, Section of Paediatric Dentistry, University of Naples, Federico II, Naples 80131, Italy;Department of Biology, Complesso Universitario di Monte Sant’Angelo, Cupa Nuova Cintia, 21-80126-Napoli, University of Naples, Federico II, Naples 80126, Italy;

关键词: Stevia rebaudiana Bertoni;    dental caries;    sweetener;   

DOI  :  10.3390/molecules21010038

来源: mdpi

【 摘 要 】

Stevia rebaudiana Bertoni is a small perennial shrub of the Asteraceae (Compositae) family that is native to South America, particularly Brazil and Paraguay, where it is known as “stevia” or “honey leaf” for its powerful sweetness. Several studies have suggested that in addition to their sweetness, steviosides and their related compounds, including rebaudioside A and isosteviol, may offer additional therapeutic benefits. These benefits include anti-hyperglycaemic, anti-hypertensive, anti-inflammatory, anti-tumor, anti-diarrheal, diuretic, and immunomodulatory actions. Additionally, critical analysis of the literature supports the anti-bacterial role of steviosides on oral bacteria flora. The aim of this review is to show the emerging results regarding the anti-cariogenic properties of S. rebaudiana Bertoni. Data shown in the present paper provide evidence that stevioside extracts from S. rebaudiana are not cariogenic. Future research should be focused on in vivo studies to evaluate the effects on dental caries of regular consumption of S. rebaudiana extract-based products.

【 授权许可】

CC BY   
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