Characterization of lymphoid follicles with red ring signs as first manifestation of early Crohn’s disease by conventional histopathology and confocal laser endomicroscopy

International Journal of Clinical and Experimental Pathology

Abbas Agaimy¹  Hermann Kessler¹  Markus F Neurath¹  Martin Raithel¹  Ekaterina Krauss¹  Jonas Mudter¹  Arndt Hartmann¹  Ulrike Schulz¹  Helmut Neumann¹ 

关键词: Endomicroscopy;    CLE;    red ring sign;    Crohn`s disease;    lymphoid hyperplasia;    inflammatory bowel disease;    ulcerative colitis;    lymphoid follicle;    pathology;   

DOI  :  

学科分类：生理学与病理学

来源: e-Century Publishing Corporation

【 摘 要 】

Clinical observations suggest that the lymphoid follicles (LFs) may play a crucial role in the pathogenesis of inflammatory bowel disease (IBD), especially in Crohn’s disease (CD) as the site of initial mucosal inflammation. The aim of this study was to compare the morphology of LFs in CD, ulcerative colitis (UC) and control patients using confocal laser endomicroscopy (CLE) in correlation to histological and immunohistochemical findings of biopsies.

【 授权许可】

Unknown