Listeria infection in Chinese pregnant women and neonates from Shandong

International Journal of Clinical and Experimental Medicine

Yanhua Xu¹  Qiurong Xie¹  Jun Lv¹  Zhenli Qin¹ 

关键词: Listeria;    neonates;    serotype;    MLST;   

DOI  :  

学科分类：医学（综合）

来源: e-Century Publishing Corporation

【 摘 要 】

Objective: This study aims to investigate the characters of pregnant women and neonates with listeria monocytogenes infections (L. monocytogenes) in Shandong of China. Method: Pregnant women with premature delivery or prenatal fever were recruited in 2013. Bacterial culture was performed for the umbilical cord blood and placental swab after delivery. The strains isolated were then analyzed for the virulence factors and classified based on the serotype and MLST typing. Results: Four cases (0.34‰) of the neonates were identified with listeriosis. Prenatal fever was observed in mothers of all infected neonates. The pathological examination of placenta showed non-specific inflammatory manifestations and two serotypes including 1/2b and 4b were detected. Six kinds of virulence factors including hly, inlA, actA, plcB, prfA and iap were all identified in the inflected neonates. Conclusion: The results suggested that mother-to-infant was an important transmission mode for listeria. Antibiotic treatment, bacterial culture and placenta pathological examination were highly recommended in the diagnosis and treatment of listeriosis.

【 授权许可】

Unknown