International Journal of Clinical and Experimental Medicine | |
Relationship between intima-media thickness and bone mineral density in postmenopausal women: a cross-sectional study | |
Afshin Mohammadi1  Yousef Rosta1  Tooraj Maleki-Miandoab1  Kamran Shateri1  Mohammad Ghasemi-rad1  Emal Lesha1  Farhad Behzadi1  | |
关键词: Bone mineral density; carotid intima media thickness; postmenopausal women; osteoporosis; | |
DOI : | |
学科分类:医学(综合) | |
来源: e-Century Publishing Corporation | |
【 摘 要 】
Background: Osteoporosis and atherosclerosis are two conditions that confer the major cause of mortality and morbidity in postmenopausal women. Several studies have suggested that these two conditions are negatively correlated by a common pathway. The aim of our study was to show a relationship between bone mineral density (BMD) and carotid intima media thickness (CIMT), as two factors that are directly related to osteoporosis and atherosclerosis respectively. Methods: The study group consisted of 136 postmenopausal women that presented at the Radiology Clinic of our hospital for BMD measurements. The CIMT was measured using High Resolution B mode Ultrasonography; BMD was measured at the lumbar spine and femoral neck using Dual-energy X-Ray Absorptiometry. Results: The mean IMT value in osteoporotic women (0.7±0.1 mm) was significantly higher compared to non-osteoporotic women (0.6±0.1 mm, P < 0.001). A significant negative correlation was found between CIMT and the T score of lumbar spine (r=-0.35; P < 0.001) and femoral neck (r=-0.23, P < 0.001), as well as Z score of the lumbar spine (r=-0.27, P=0.004). No significant correlation was found between CIMT and Z score of the femoral neck. Conclusion: Our study shows that bone mineral density and carotid intima media thickness are negatively correlated, thus showing a possible relationship between osteoporosis and atherosclerosis. However, more research is necessary to determine the pathway that connects these two conditions.
【 授权许可】
Unknown
【 预 览 】
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RO201912140864017ZK.pdf | 519KB | download |