Assessment of hepatic steatosis on contrast enhanced computed tomography in patients with colorectal cancer

International Journal of Clinical and Experimental Medicine

Elif Aktas¹  Ayse Kefeli¹  Ozgur Yeniova¹  Okan Yildirim¹  Fatih Buyukcam¹  Metin Uzman¹  Sebahat Basyigit¹  Bora Aktas¹  Aslihan Mete Yildirim¹  Burcu Sahin¹  Bilgin Kadri Aribas¹  Baris Yilmaz¹ 

关键词: Colorectal cancer;    fatty liver;    hepatosteatosis;    computed tomography;   

DOI  :  

学科分类：医学（综合）

来源: e-Century Publishing Corporation

【 摘 要 】

Aims: Non-alcoholic fatty liver disease is often seen in patients with colorectal cancer. Insulin resistance and metabolic syndrome are related to increased risk of colorectal cancer. The aim of this study was to quantitatively determine the relationship between non-alcoholic fatty liver disease and colorectal cancer with the examination of routine abdominopelvic computed tomography images taken for staging. Methods: A retrospective evaluation was made of the colonoscopy and histopathology reports of 1630 patients who presented for a scanning or diagnostic colonoscopy examination. Colorectal cancer was determined histopathologically in 129 cases. Colorectal cancer patients with distant metastasis or additional malignancies were excluded from the study. A total of 105 patients met the criteria and were included in the study. A control group was formed of 94 patients with no history of cancer. The liver density on abdominopelvic computed tomography and serum transaminase values were recorded for the patients and compared with those of the control group. Results: The groups were similar in respect of age, gender and aspartate aminotransferase levels. Although not statistically significant, the alanine aminotransferase levels of the patient group were high compared to the control group. The liver density on computed tomography was statistically significantly lower in the patient group than in the control group. Conclusion: The liver density measurement on contrast abdominopelvic computed tomography of colorectal cancer patients was low, which is consistent with non-alcoholic fatty liver disease.

【 授权许可】

Unknown