Effects of different inhaled oxygen concentration and end-expiratory positive pressure on Pa-etCO2 in patients undergoing gynecological laparoscopic surgery

International Journal of Clinical and Experimental Medicine

Guiqi Geng¹  Jingyi Hu¹  Shaoqiang Huang¹ 

关键词: FiO2;    PEEP;    PaCO2;    PetCO2;    laparoscopic surgery;   

DOI  :  

学科分类：医学（综合）

来源: e-Century Publishing Corporation

【 摘 要 】

There is some disagreement about whether the PetCO₂ is reliable in predicting the PaCO₂ in laparoscopic procedures with CO₂ inflation. The aim of the present study is to measure the Pa-etCO₂ differences over time in healthy patients undergoing gynecological laparoscopic surgery with different ventilation methods. Methods: After intubation, patients were randomized into three groups. The patients in group A were ventilated with air/O₂ (FiO₂ = 50%) and supplied with PEEP (5cmH₂O). The patients in group B were ventilated with 50% oxygen while the patients in group C were ventilated with 100% oxygen. All patients were conducted with volume-controlled ventilation. PetCO₂ and PaCO₂ were measured at baseline, one minute after intubation, every 30 min thereafter and 5 minutes after deflation of pneumoperitoneum. Results: The differences in Pa-etCO₂ between groups A, B and C were insignificant one minute after intubation. The Pa-etCO₂ in group B and C significantly increased compared with that in group A at other time points after intubation. Conclusion: Oxygen concentration and positive end-expiratory pressure could affect Pa-etCO₂ in laparoscopic surgery patients.

【 授权许可】

Unknown