Leaks can dramatically decrease FiO2 on home ventilators: a bench study

BMC Research Notes

Eric Meaudre¹  Bruno Palmier¹  Julien Bordes¹  Bertrand Prunet¹  Pierre Esnault¹  Yves Asencio¹  Erwan Daranda¹  Philippe Goutorbe¹ 

[1] Emergency, Anesthesia and ICU Departement, Military Teaching Hospital Sainte Anne, Boulevard Sainte Anne, Toulon 83000, France

关键词: FiO2;    COPD;    Home ventilation;    Leaks;    NIV;   

Others  :  1142118
DOI  :  10.1186/1756-0500-6-282

 received in 2013-05-06, accepted in 2013-07-18,  发布年份 2013

【 摘 要 】

Background

Long term oxygen therapy improves survival in hypoxemic patients with chronic obstructive pulmonary disease (COPD). Because pressure support ventilation with a home care ventilator is largely unsupervised, there is considerable risk of leakage occurring, which could affect delivered FiO₂. We have therefore conducted a bench study in order to measure the effect of different levels of O₂ supply and degrees of leakage on delivered FiO₂. Ventilator tested: Legendair® (Airox™, Pau, France). Thirty-six measures were performed in each four ventilators with zero, 5 and 10 l.min-1 leakage and 1,2,4 and 8 l O2 flow.

Findings

FiO₂ decreased significantly with 5 l.min-1 leakage for all O2 flow rates, and with 10 l.min-1 at 4 and 8 l.min-1 O2.

Conclusion

During application of NIV on home ventilators, leakage can dramatically decrease inspired FiO2 making it less effective. It is important to know the FiO2 dispensed when NIV is used for COPD at home. We would encourage industry to develop methods for FiO2 regulation Chronic use of NIV for COPD with controlled FiO2 or SpO2 requires further studys.

【 授权许可】

   
2013 Goutorbe et al.; licensee BioMed Central Ltd.

【 图 表 】

Figure 1.

Figure 2.

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