Predictors of Tuberculosis in HIV/AIDS Patients Referred to Behavioral Diseases Consultation Center: A Registry-Based Study in Abadan, Southwest of Iran

lranian journal of Clinical Infectious Diseases

Shahab Rezaeian²  Mehran Yari³  Salman Khazaei⁴  Somayeh Khazaei⁶  Ali Asghar Valipour³  Erfan Ayubi¹  Leila Molaeipoor⁵ 

[1] Department of Epidemiology, School of Public Health, Shahid Beheshti University of Medical Sciences, Tehran, Iran Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran;Social Determinant of Health Research Center, Kurdistan University of Medical Sciences, Sanandaj, Iran;Student Research Committee, Abadan School of Medical Sciences, Abadan, Iran;Department of Epidemiology, School of Public Health, Hamadan University of Medical Sciences, Hamadan, Iran;Department of Epidemiology, Pasteur Institute of Iran, Tehran, Iran;Department of Operating Room, Rafsanjan University of Medical Sciences, Rafsanjan, IR Iran

关键词: Predictors;    Tuberculosis;    HIV/AIDS;    Cross-Sectional Study;    Iran;   

DOI  :  10.17795/semj41542

学科分类：基础医学

来源: Shiraz University of Medical Sciences

【 摘 要 】

Background:Intheworld,itisestimatedthat36.9millionpeoplearelivingwithHIV(PLHIV).Tuberculosis(TB)remainsastheleadingcauseofdeathamongPLHIV.ThisstudyaimedtodeterminethepredictorsofTBamongHIVpositivepatients.Methods:Thiscross-sectionalstudywasbasedonthedatafrom366patientswithHIV/AIDSacquiredfrom2010to2013inAbadanandKhorramshahrcities,southwestofIran.Demographicandclinicaldatawereobtainedfrompatients’medicalrecordsinAbadanandKhorramshahrtriangularclinics.UnivariateandmultivariablebinarylogisticregressionmodelswereusedtoidentifyTBpredictorsamongHIV/AIDSpatients.Results:TheprevalenceofTBpatientswas21.9%amongHIVpatients.About57.4%ofthepatientswerebelow35yearsofage,andmostofthem(85.5%)weremale.UnivariatelogisticregressionshowedastatisticallysignificantassociationbetweentheoccurrenceofTBandexplanatoryvariablesincludingsex,imprisonmenthistory,HCVandHBVstatus,addiction,stageofdisease,CD4cellandTLC(Totallymphocytecount)count.Inmultivariateanalysis,beingaddicted(adjustedOR=7.03,95%CI:1.28,38.66)andpositiveHBV(adjustedOR=4.28,95%CI:1.53,12.00)wereassociatedwithincidenceofTBafteradjustingforage,sex,phaseatdiagnosis,addictionandHBVstatus.Conclusions:AddictionandHBVinfectioncanbeconsideredaspredictorsofincidenceofTBinHIV/AIDSpatientsthenearlydiagnosisofTBespeciallyinhigher-riskgroups,suchasthosewithaddictionandHBVinfectionisrecommended.

【 授权许可】

Unknown