期刊论文详细信息
lranian journal of Clinical Infectious Diseases
New Therapeutic Modalities in Liver Inflammation and Fibrosis
A Najafi2  M Mojtahedzadeh4  MR Khajavi3  F Fallahian1 
[1] Associate Professor, Department of Intensive Care Unit and Anesthesiology,;Professor of Pharmacotherapy, Sina Hospital, Tehran Uni-versity of Medical Sciences. Iran.;Professor of Pharmacotherapy, Sina Hospital, Tehran Uni-versity of Medical Sciences. Iran.
关键词: Hepatitis;    Inflammation pathways;    Treatment modalities;    Stem cell trans-plantation;   
DOI  :  10.17795/semj20483
学科分类:基础医学
来源: Shiraz University of Medical Sciences
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【 摘 要 】

Understandingthemolecularandcellularmechanismsunderlyingliverinflammationandfibrosiswouldfacilitatetodesignappropriatetherapeuticinterventionstohaltorreversetheprocessofliverfibrosis.Areviewofliteraturewasperformedin2010tosummarizescientificreportsoninflammationpathwaysofhepatitis.ArticlesindexedinthePubMeddatabaseduringrecenttenyearssearchedforhepatitis,inflammationpathways,treatmentmodalities,andstemcelltransplantationtoinvestigatecellularandmolecularpathwaysandbiologicroleofgrowthfactors,cytokines,andmediatorsengagedinliverinflammationfacilitatethede-velopmentofpharmacologicalintervention.Thismanuscriptreviewssomerecentscientificadvances,andtherapeuticinterventionsinliverinflammation,andfibrosis

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