Antibacterial Activity of Saponin Isolated from the Leaves of Solanum trilobatum Linn

Journal of Applied Biological Sciences

Krishnan KANNABIRAN¹  Ramalingam R. THANIGAIRASSU¹  Venkatesan Gopiesh KHANNA¹ 

关键词: Medicinal plant;    antibacterial activity;    bactericidal drug;    disc diffusion;    agar well diffusion;   

DOI  :  

学科分类：生物科学（综合）

来源: Nobel Bilim ve Arasirma Merkezi/Nobel Science and Research Cente

【 摘 要 】

Thisstudywasdesignedtotesttheantimicrobialpotentialofethanol,acetoneandethylacetateextractsofleaves,fruitsandflowersofSolanumtrilobatumandpuresaponinfractionextractedfromtheleavesagainstselectedbacterialstrains,Staphylococcusaureus,Escherichiacoli,PseudomonasaeruginosaandKlebsiellapneumoniae.Theantibacterialactivitywastestedbyagardiscdiffusionandagarwelldiffusionmethod.Theplantpartstestedwereextractedwithethanol,acetoneandethylacetate.Almostalltheorganicsolventextractsexhibitedgoodinhibitoryeffectagainsttestedbacterialpathogens.ThemostsusceptibleGram-positivebacterialspecieswasS.aureus,whilethemostsusceptibleGram-negativebacteriawasP.aeruginosa.Puresaponinfractionexhibitedremarkableantibacterialactivitywhencomparedtocrudeextracts.Theantibacterialactivityofextractswasfoundtobecomparativelyhigherthanthestandardantibioticsusedinthisstudy.Theseresultsprovideevidencefortheantagonisticactivityofsteroidalsaponinagainsttestedbacterialpathogens.Further,itcouldbedevelopedasabactericidaldrugtobeusedastherapeuticagentagainstbacterialinfections.

【 授权许可】

Unknown