Journal of Applied Biological Sciences | |
Antibacterial Activity of Saponin Isolated from the Leaves of Solanum trilobatum Linn | |
Krishnan KANNABIRAN1  Ramalingam R. THANIGAIRASSU1  Venkatesan Gopiesh KHANNA1  | |
关键词: Medicinal plant; antibacterial activity; bactericidal drug; disc diffusion; agar well diffusion; | |
DOI : | |
学科分类:生物科学(综合) | |
来源: Nobel Bilim ve Arasirma Merkezi/Nobel Science and Research Cente | |
【 摘 要 】
Thisstudywasdesignedtotesttheantimicrobialpotentialofethanol,acetoneandethylacetateextractsofleaves,fruitsandflowersofSolanumtrilobatumandpuresaponinfractionextractedfromtheleavesagainstselectedbacterialstrains,Staphylococcusaureus,Escherichiacoli,PseudomonasaeruginosaandKlebsiellapneumoniae.Theantibacterialactivitywastestedbyagardiscdiffusionandagarwelldiffusionmethod.Theplantpartstestedwereextractedwithethanol,acetoneandethylacetate.Almostalltheorganicsolventextractsexhibitedgoodinhibitoryeffectagainsttestedbacterialpathogens.ThemostsusceptibleGram-positivebacterialspecieswasS.aureus,whilethemostsusceptibleGram-negativebacteriawasP.aeruginosa.Puresaponinfractionexhibitedremarkableantibacterialactivitywhencomparedtocrudeextracts.Theantibacterialactivityofextractswasfoundtobecomparativelyhigherthanthestandardantibioticsusedinthisstudy.Theseresultsprovideevidencefortheantagonisticactivityofsteroidalsaponinagainsttestedbacterialpathogens.Further,itcouldbedevelopedasabactericidaldrugtobeusedastherapeuticagentagainstbacterialinfections.
【 授权许可】
Unknown
【 预 览 】
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RO201912090818415ZK.pdf | 220KB | download |