Numerical Study on the Morphology and Mechanical Role of Healthy and Osteoporotic Vertebral Trabecular Bone

Journal of Biomechanical Science and Engineering

Miguel CLANCHE¹  Naoki TAKANO³  Yuto YOSHIWARA⁴  Khairul Salleh BASARUDDIN⁴  Takayoshi NAKANO² 

[1]Ecole Centrale de Nantes

[2]Division of Materials and Manufacturing Science, Graduate School of Engineering, Osaka University

[3]Department of Mechanical Engineering, Keio University

[4]Graduate School of Science and Technology, Keio University

关键词: Vertebra;    Trabecular Bone;    Numerical Analysis;    Homogenization Method;    Microsccopic Stress;   

DOI  :  10.1299/jbse.6.270

来源: Japan Society of Mechanical Engineers

【 摘 要 】

References(22)Cited-By(4)This study presents a numerical methodology to clarify the morphology of complex trabecular network architecture in human lumbar vertebra by means of the new post-processing technique for calculated microscopic stress by the homogenization method. Micro-CT image-based modeling technique is used and careful but intuitive and easy-to-use method for microstructure model, in other words region of interest (ROI), is also presented. The macroscopic homogenized properties that include not only the Young's moduli but also shear moduli could explain the difference of morphology between healthy and osteoporotic bones. This paper focuses on the change of degree of anisotropy. Then, the microscopic stress under three basis load cases was analyzed. In this analysis, the homogenization method has a merit in the computational cost. The trabeculae are classified into eight groups from the viewpoint of load bearing function against three loading conditions in the proposed post-processing of numerical results. It contributes to the understanding of the mechanical role of trabecular bone in vertebra. The primary trabecular bone that has been supposed to support the self-weight and secondary bone that connects the primary bone are successfully visualized. The discussion on the mechanical role of plate-like trabecular bone in the load path network system is also highlighted.

【 授权许可】

Unknown