Achitecture of Porous Hydroxyapatite Scaffolds Using Polymer Foam Process

Journal of Biomechanical Science and Engineering

Jeong-Jung OAK¹  Takashi GOTO¹  Akihisa INOUE¹  Hisamichi KIMURA¹  Seog-Young YOON²  Zin-Kook KIM² 

[1] Institute for Materials Research, Tohoku University;School of Materials Science and Engineering, Pusan National University

关键词: Porous;    Hydroxyapatite;    Scaffold;    Polymer;    Foaming;   

DOI  :  10.1299/jbse.4.377

来源: Japan Society of Mechanical Engineers

【 摘 要 】

References(17)Cited-By(5)Newly approach using the formation process of polymer foam is introduced in this study to prepare porous hydroxyapatite (HAp) scaffolds for bone tissue engineering applications, which could provide a better control over the microstructures of scaffolds and enhance their mechanical properties. The scaffolds prepared have an open, relatively uniform and interconnected porous structure with a pore size ranging 50 to 300 µm. A compressive strength of 5 MPa for the scaffolds with HAp content 80 wt% and higher porosity of 77% was achieved. The pore morphology and size of the scaffolds were characterized using a scanning electron microscopy. X-ray diifraction was used to determine the crystal structure. Scaffolds with desired porosity, pore size, and geometry could be prepared by using the formation process of polymer foam with controlling process parameters.

【 授权许可】

Unknown