Analysis of Three-Dimensional Characteristics in Tumor Morphology

Journal of Biomechanical Science and Engineering

Hiroki SHIRATO²  Hiroshi TAGUCHI²  Shigeru TADANO¹  Seishin TAKAO¹ 

[1] Division of Human Mechanical Systems and Design, Graduate School of Engineering, Hokkaido University;Department of Radiology, Hokkaido University Graduate School of Medicine

关键词: Tumor Geometry;    Surface Geometry Map;    Radiotherapy;    Therapeutic Response;   

DOI  :  10.1299/jbse.4.221

来源: Japan Society of Mechanical Engineers

【 摘 要 】

References(7)Cited-By(1)Precise assessment of therapeutic response in radiotherapy has been an important issue in the field of radiation oncology. This study proposed a methodology to evaluate therapeutic response based on tumor geometries. Three-dimensional (3D) tumor shapes were obtained from follow-up CT scans taken once a week throughout the treatment period. Tumor geometries were represented in two-dimensional (2D) surface geometry maps. These maps indicated the distances from the tumor center to surface at each azimuthal and horizontal angle by colors, in order to represent the characteristics of tumor morphologies. This method was applied to three clinical cases of head and neck cancer. The changes of tumor geometries could be represented visually and quantitatively using surface geometry maps. These maps provided valuable information about tumors for accurate diagnosis of tumor response to radiotherapy.

【 授权许可】

Unknown