期刊论文详细信息
The Japanese Journal of Pharmacology
Salivary Amylase Activity of Rats Fed a Low Calcium Diet
Shigeki Sakata1  Makoto Okamura1  Mitsuko Shinohara1  Kiyoshi Ohura1  Pao-Li Wang1  Noboru Murakawa1  Masaki Endo1  Michiharu Daito2  Shinya Shirasu2 
[1] Department of Pharmacology, Osaka Dental University;Department of Pediatric Dentistry, Osaka Dental University
关键词: Saliva;    Amylase;    Low Ca diet;    Parotid gland;    Cyclic AMP;   
DOI  :  10.1254/jjp.78.279
学科分类:药理学
来源: Nihon Yakuri Gakkai Henshuubu / Japanese Pharmacological Society
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【 摘 要 】

References(16)Cited-By(4)Wistar strain rats fed low calcium diets (1, 2, 3, 4, 6 and 8 weeks) exhibited changes in secretory function of whole saliva. In particular, there were changes in salivary flow rate, total salivary protein, amylase enzyme activity, salivary amylase content and the level of cyclic AMP in the parotid gland acinar cell. Although there were no changes for the first 3 weeks, the levels increased at week 4 and decreased at week 6. The wet weight of the parotid gland started to decrease at week 4. These results suggest that when fed low calcium diets for long periods of time, rats develop defective salivary secretion.

【 授权许可】

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