Relationship Between Nuclear Ribonucleoprotein Arrangement and Cell Proliferation in Burkitt Lymphoma Cells

Cell Structure and Function

Amelia Cataldi¹  Renato Lisio¹  Iole Robuffo²  Sebastiano Miscia¹ 

[1] Istituto di Morfologia Umana Normale, Università di Chieti;Istituto di Citomorfologia Normale e Patologica del CNR

关键词: peroxisome;    peroxisome proliferator;    PPAR;    orphan receptor;    hepatocarcinogenesis;   

DOI  :  10.1247/csf.18.279

学科分类：分子生物学，细胞生物学和基因

来源: Japan Society for Cell Biology

【 摘 要 】

References(37)Cited-By(1)The presence of body-like structures in nuclei from interferon alpha-treated Daudi cells has been shown on the ultrastructural level, by the use of different staining methods. The degree of their rearrangement in the nucleoplasm seems to be dependent on the time of interferon treatment. Since this morphological EVIDENCE has been found to be preceded by a slowing down of RNA transcriptional machinery early upon the interferon administration, it is speculated that interferon generated signals might lead to RNP granule accumulation in the nucleus and a consequent arrangement into defined structures.

【 授权许可】

Unknown