A Study Of The Clinical and BiochemicalProfile Of Acute Viral Hepatitis

International Journal of Biomedical and Advance Research

Sangram Mangudkar¹  Varsha Shirish Dabadghao¹  Suresh Kumar Sharma¹  Ram Barure¹ 

关键词: acute viral hepatitis;    hepatitis E;    hepatitis B;    hepatitis C;    hepatitis A;    hepatitis D;   

DOI  :  10.7439/ijbar.v6i10.2350

学科分类：药学、药理学、毒理学（综合）

来源: Scholar Science Journals

【 摘 要 】

Aim:This study was performed to compare the clinical, biochemical and etiological properties of acute viral hepatitis (AVH) and to compare clinical and laboratory parameters of faeco-oraly transmitted hepatitis: hepatitis A+ hepatitis E (A+E) with hematologicaly transmitted: hepatitis B, C, D (B+C+D) hepatitis. Material and Methods:Biochemical and clinical data were collected from 40 patients with AVH. They were tested for hepatitis B surface antigen (HBsAg), IgM anti-Hepatitis A virus (HAV), IgM anti-HBc (hepatitis B core antigen), IgM anti- hepatitis D (HDV), or IgM anti- hepatitis C (HCV). Finally X 2test was used to analysis of data. Results:Most patients were young adults and presented with jaundice and other constitutional features, although anicteric hepatitis was also seen. Hepatitis E was the most common AVH. Malaise, fever, icterus, vomiting and nausea were significantly more in Hepatitis A +E compared with Hepatitis B + C in acute course. Serum bilirubin both total and direct was significantly elevated in hepatitis A + E compared with Hepatitis B + C in acute course. Conclusions:Hepatitis E was the most common AVH .There were some differences in clinical and laboratory findings regarding to the etiology but it does not necessarily distinguish one cause of hepatitis from another.

【 授权许可】

CC BY