Mucosal leishmaniasis: epidemiological and clinical aspects

Revista Brasileira de Otorrinolaringologia

Lessa, Marcus Miranda¹  Carvalho, Edgar M.¹  Castro, Thomas W. N.¹  FMUSP¹  Lessa, Hélio Andrade¹  Machado, Paulo¹  Universidade de Graz, Áustria¹  Universidade Federal da Bahia¹  Scherifer, Albert¹  Oliveira, Adja¹ 

关键词: granulomatous disease;    leishmaniasis;    mucosal leishmaniasis.;   

DOI  :  10.1590/S0034-72992007000600016

学科分类：医学（综合）

来源: Associacao Brasileira de Otorrinolaringologia e Cirurgia Cervicofacial

【 摘 要 】

Leishmaniasis has been documented in several countries, with an estimated prevalence of 12 million people and an incidence at around 400,000 new cases per year. Leishmaniasis in the New World is one the major endemic diseases in Brazil and Latin America. OBJECTIVE: The aim of this study was to add to the current knowdlegde on mucosal leishmaniasis, bringing the experience of the Imunology and Otolaryngology Departments in the Professor Edgar Santos University Hospital of the Federal University of Bahia. CONCLUSION: Cutaneous leishmaniasis is the most common form of New World Leishmaniasis; mucosal legions may occur simultaneously or after years of disease. Mucosal leishmaniasis is caused mainly by L. braziliensis braziliensis; although the nasal mucosa is the most affected area, lesions may be found on the lips, mouth, pharynx and larynx. In addition to parasite-related factors, the host immune response may be involved in the pathogenicity of lesions in mucosal leishmaniasis.

【 授权许可】

Unknown