Relationship between the levels of volatile sulfur compounds with the levels of RANKL and OPG in patients with moderate or severe periodontitis: A cross sectional study

Revista clínica de periodoncia, implantología y rehabilitación oral

Ramírez Lobos, V¹  Inostroza Silva, C¹  Prieto Damm, D¹  Sanz Ruiz, A¹  Universidad de los Andes, Chile¹  Chaparro Padilla, A¹ 

关键词: Halitosis;    periodontitis;    volatile sulfur compounds;    RANKL and OPG.;   

DOI  :  10.4067/S0719-01072013000100004

来源: Sociedad de Periodoncia de Chile

【 摘 要 】

Background: The effect of the Volatile Sulfur Compounds (VSC) on the periodontal tissues, specifically at the RANKL/OPG level has not been elucidate and there is little literature published on this subject. Aim: To explore if the VSC levels measured in the oral cavity of patients with moderate or severe chronic periodontitis are correlated with the expression of RANKL and OPG at the gingival fluid level (GF). Method: A cross-sectional study was conducted with 71 patients referred by the Universidad de los Andes’s dentistry diagnosis department. After undergoing full-mouth periodontal exam, levels of CVS were recorded using a sulfur monitor and then GF was extracted to assess RANKL and OPG levels with ELISA. Data was analyzed with Spearman correlation test. Results: The correlation (R) between the VSC and the GF levels was 0.098 with a p value = 0.41; -0.084 with a p value = 0.48 y 0.067 with a p value = 0.57 respectively. Conclusions: This study could not demonstrate if there is a relation between the VSC levels and the expression of RANKL and OPG in the GF in patients with chronic periodontitis.

【 授权许可】

Unknown