Oral microbiome as a co-mediator of halitosis and periodontitis: a narrative review

Frontiers in Oral Health

Oral Health

Yeon-Hee Lee¹  Ji-Youn Hong² 

[1] Department of Orofacial Pain and Oral Medicine, Kyung Hee University School of Dentistry, Kyung Hee University Medical Center, Seoul, Republic of Korea;Department of Periodontology, Periodontal-Implant Clinical Research Institute, School of Dentistry, Kyung Hee University, Seoul, Republic of Korea;

关键词: halitosis;    oral malodor;    periodontitis;    oral microbiome;    volatile sulfur compounds;    bacteria;   

DOI  :  10.3389/froh.2023.1229145

 received in 2023-05-26, accepted in 2023-08-18,  发布年份 2023

来源: Frontiers

【 摘 要 】

ObjectiveHalitosis or oral malodor is an unpleasant odor from the oral cavity. However, although patients with periodontitis often complain of halitosis, their relationship has not been fully elucidated. We reviewed previous literature based on the hypothesis that the relationship between halitosis and periodontitis is mediated by the oral microbiome.Materials and methodsThis narrative review sought to provide insight into the causative role of the oral microbiome in influencing halitosis and periodontitis. In addition, we tried to deepen knowledge related to the relationship between halitosis and periodontitis generated by the oral microbiome accumulated over the past 40 years.ResultsFrom 1984 to 2023, a total of 106 papers that carefully and scientifically dealt with halitosis and periodontitis were included in this narrative review. Based on previous results, halitosis and periodontitis were closely related. For decades, researchers have taken an intriguing approach to the question of whether there is a relationship between halitosis and periodontitis. Central factors in the relationship between halitosis and periodontitis include volatile sulfur compounds (VSCs), the oral microbiota that produce VSCs, and the inflammatory response.ConclusionsTaken together, the more severe periodontitis, the higher the level of VSC in halitosis, which may be mediated by oral microbiome. However, the relationship between the occurrence, maintenance, and exacerbation of periodontitis and halitosis is not a necessary and sufficient condition for each other because they are complex interplay even in one individual.

【 授权许可】

Unknown   
© 2023 Lee and Hong.