A population-based study of the epidemiology of pancreatic cancer: a brief report

Current Oncology

M.E. Trudeau¹  C.C. Earle¹  M.C. Cheung¹  N. Goyert¹  N. Liu²  J.S. Hoch⁵  R.S. Raju¹  N. Coburn¹  N. Mittmann⁴  S.J. Seung⁷  W.K. Evans³  N.B. Leighl⁸  J.M. Porter²  K.N. Dainty⁶ 

[1] Odette Cancer Centre, Sunnybrook Health Sciences Centre;Institute for Clinical Evaluative Sciences;McMaster University;Health Outcomes and PharmacoEconomics (HOPE) Research Centre,Sunnybrook Research Institute, University of Toronto, Western University;Applied Research in Cancer Control, Cancer Care Ontario;Keenan Research Centre of the Li Ka Shing Knowledge Institute, St. Michael's Hospital;Health Outcomes and PharmacoEconomics (HOPE) Research Centre, Sunnybrook Research Institute;Princess Margaret Cancer Centre, University Health Network

关键词: Pancreatic adenocarcinoma;    retrospective analyses;    population studies;    outcomes;   

DOI  :  

学科分类：肿瘤学

来源: Multimed, Inc.

【 摘 要 】

ObjectiveAdministrative data are used to describe the pancreatic cancer (pcc) population. The analysis examines demographic details, incidence, site, survival, and factors influencing mortality in a cohort of individuals diagnosed with pcc. MethodsIncident cases of pcc diagnosed in Ontario between 1 January 2004 and 31 December 2011 were extracted from the Ontario Cancer Registry. They were linked by encrypted health card number to several administrative databases to obtain demographic and mortality information. Descriptive, bivariate, and survival analyses were conducted. ResultsDuring the period of interest, 9221 new cases of pcc (4548 in men, 4673 in women) were diagnosed, for an age-adjusted standardized annual incidence in the range of 8.6–9.5 per 100,000 population. Mean age at diagnosis was 70.3 } 12.5 years (standard deviation). Five-year survival was 7.2% (12.8% for those <60 years of age and 3.6% for those >80 years of age). Survival varied by sex, older age, rural residence, lower income, site of involvement in the pancreas, and presence of comorbidity. ConclusionsThe mortality rate in pcc is exceptionally high. With an increasing incidence and a mortality positively associated with age, additional support will be needed for this highly fatal disease as demographics in Ontario continue to trend toward a higher proportion of older individuals. 

【 授权许可】

Unknown