Quantification of the uranium concentration in human urine by inductively coupled plasma-sector field mass spectrometry (ICP-SFMS)

Química Nova

Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas, Madrid, Spain¹  Fernández, Marta¹  Yllera, Abel¹  Hernández-Mendoza, Héctor¹  Instituto Nacional de Investigaciones Nucleares, Ocoyoacac, México¹  Conde, Estefanía¹ 

关键词: uranium;    urine;    ICP-MS.;   

DOI  :  10.1590/S0100-40422013000600021

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

In this study, the validation of a method for analyzing the uranium (U) concentration in human urine samples by inductively coupled plasma-sector field mass spectrometry (ICP-SFMS) was conducted. PROCORAD (the Association for the Promotion of Quality Control in Radiotoxicological Analysis) provided two urine samples spiked with unknown contents of U (Sample A = 33.6 ± 1.0 µg/L and Sample B = 3.3 ± 0.1 µg/L) and one unspiked sample as a blank. The analyses were directly performed on the diluted urine samples (dilution factor = 1:20) in 5% v/v HNO3. The results obtained by ICP-SFMS corresponded well with the reference values, and the limits of detection were 235U = 0.049 × 10-3 µg/L and 238U = 7.37 × 10-3 µg/L. The ICP-SFMS technique has been shown to be successful in the analysis of the U concentration in human urine samples and for the quantification of isotopic ratios.

【 授权许可】

Unknown