Chemical composition and antimicrobial activity of leaf essential oil from Piper malacophyllum (C. Presl.) C. DC.

Química Nova

Cruz, Alexandre Bella¹  Universidade do Vale do Itajaí, Itajaí, Brasil¹  Cruz, Rosana Cé Bella¹  Dalmarco, Eduardo Monguilhott¹  Guedes, Alessandro¹  Schmit, Ana Paula¹  Rebelo, Ricardo Andrade¹  Universidade Federal de Santa Catarina, Florianópolis, Brasil¹  Steindel, Mário¹  Nunes, Rebeca Körting¹  Santos, Thalita Gilda¹  Universidade Regional de Blumenau, Blumenau, Brasil¹  Gasper, André Luís de¹ 

关键词: Piper malacophyllum;    antimicrobial evaluation;    antifungal activity.;   

DOI  :  10.1590/S0100-40422012000300007

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

This work reports the chemical composition as well as the antibacterial, antifungal and antiparasitic activities of the leaf essential oil from Piper malacophyllum. The oil was extracted by hydrodistillation and analyzed by GC-FID, GC-MS and polarimetry. Among the 28 compounds identified, (+)-camphor was the major constituent. The essential oil showed activity against most of the microorganisms tested, especially antifungal action, with a MIC of 500 µg mL-1 against Trichophyton mentagrophytes and Cryptococcus neoformans. This is the first study reporting the composition and biological properties of leaf essential oil from P. malacophyllum.

【 授权许可】

Unknown