Chemical composition and antimicrobial activity of leaf essential oil from Piper malacophyllum (C. Presl.) C. DC.

Quimica nova

Steindel, Mário¹  Nunes, Rebeca Körting¹  Rebelo, Ricardo Andrade²  Dalmarco, Eduardo Monguilhott²  Guedes, Alessandro²  Santos, Thalita Gilda²  Gasper, André Luís de²  Cruz, Alexandre Bella³  Cruz, Rosana Cé Bella³  Schmit, Ana Paula³ 

[1] Universidade Federal de Santa Catarina, Florianópolis, Brasil;Universidade Regional de Blumenau, Blumenau, Brasil;Universidade do Vale do Itajaí, Itajaí, Brasil

关键词: Piper malacophyllum;    antimicrobial evaluation;    antifungal activity.;   

DOI  :  10.1590/S0100-40422012000300007

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

This work reportsthe chemical composition as well as the antibacterial, antifungal and antiparasiticactivities of the leaf essential oil from Piper malacophyllum. The oilwas extracted by hydrodistillation and analyzed by GC-FID, GC-MS and polarimetry.Among the 28 compounds identified, (+)-camphor was the major constituent. Theessential oil showed activity against most of the microorganisms tested, especiallyantifungal action, with a MIC of 500 µg mL-1 against Trichophytonmentagrophytes and Cryptococcus neoformans. This is the first studyreporting the composition and biological properties of leaf essential oil fromP. malacophyllum.

【 授权许可】

CC BY