期刊论文详细信息
Química Nova
Studies on the development of spectrophotometric method for the determination of haloperidol in pharmaceutical preparations
Rahman, Habibur1  Aligarh Muslim University, Pradesh, India1  Khatoon, Asma1  Rahman, Nafisur1 
关键词: haloperidol;    ion-pair complex;    spectrophotometry.;   
DOI  :  10.1590/S0100-40422012000200028
学科分类:化学(综合)
来源: Sociedade Brasileira de Quimica
PDF
【 摘 要 】

A spectrophotometric method based on the formation of ion-pair complex between haloperidol and eriochrome black T (EBT) at pH 1.85 has been described. The formed complex was extracted quantitatively into chloroform and measured at 510 nm. Infra red (IR) studies were performed to confirm the formation of ion-pair complex. Beer's law was obeyed in the concentration range of 2.0-9.0 µg mL-1 with molar absorptivity of 2.67 × 104 L mol-1 cm-1. The detection limit was found to be 0.18 µg mL-1. Statistical comparison of the results of the proposed method with those of the reference method shows excellent agreement and indicates no significant difference in accuracy and precision.

【 授权许可】

Unknown   

【 预 览 】
附件列表
Files Size Format View
RO201912050595620ZK.pdf 404KB PDF download
  文献评价指标  
  下载次数:6次 浏览次数:8次