Abitane diterpenoids isolation from Plectranthus barbatus

Química Nova

Braz-Filho, Raimundo¹  Universidade Estadual do Ceará, Fortaleza, Brasil¹  Machado, Maria Iracema L.¹  Matos, Francisco José de A.¹  Silva, Maria Goretti V.¹  Morais, Selene M.¹  Kentopff, Marta R.¹  Universidade Federal do Ceará, Fortaleza, Brasil¹  Albuquerque, Roberto L. de¹  Universidade Estadual do Norte Fluminense, Campos dos Goytacazes, Brasil¹ 

关键词: Plectranthus barbatus;    Labiatae;    abietane diterpenoids.;   

DOI  :  10.1590/S0100-40422007000800016

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Plectranthus barbatus is largely used in the Northeast region of Brazil by the local population for treatment of digestive problems as substitute of boldo (Pneumus boldus). Phytochemical analysis of the leaf extracts of Plectranthus barbatus (Labiatae) cultivated in this region yielded two abietane diterpenoids, cyclobubatusin (1) and barbatusin (2) and a new one named 7b-acetyl-12-deacetoxycyclobutatusin (3). The structures of the isolated compounds were established by spectral analysis, using mainly mass spectra and 1H and 13CNMR (1D and 2D). These procedures permitted the assignment of all chemical shifts in the diterpenoids.

【 授权许可】

Unknown