Abitane diterpenoids isolation from Plectranthus barbatus

Quimica nova

Morais, Selene M.¹  Braz-Filho, Raimundo²  Machado, Maria Iracema L.³  Silva, Maria Goretti V.³  Matos, Francisco José de A.³  Kentopff, Marta R.³  Albuquerque, Roberto L. de³ 

[1] Universidade Estadual do Ceará, Fortaleza, Brasil;Universidade Estadual do Norte Fluminense, Campos dos Goytacazes, Brasil;Universidade Federal do Ceará, Fortaleza, Brasil

关键词: Plectranthus barbatus;    Labiatae;    abietane diterpenoids.;   

DOI  :  10.1590/S0100-40422007000800016

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Plectranthus barbatus is largely usedin the Northeast region of Brazil by the local population for treatment of digestiveproblems as substitute of boldo (Pneumus boldus). Phytochemical analysisof the leaf extracts of Plectranthus barbatus (Labiatae) cultivated inthis region yielded two abietane diterpenoids, cyclobubatusin (1) andbarbatusin (2) and a new one named 7b-acetyl-12-deacetoxycyclobutatusin(3). The structures of the isolated compounds were established by spectralanalysis, using mainly mass spectra and 1H and 13CNMR(1D and 2D). These procedures permitted the assignment of all chemical shiftsin the diterpenoids.

【 授权许可】

CC BY