Thiosemicarbazones: preparation methods, synthetic applications and biological importance

Química Nova

Universidade Federal de Pernambuco, Recife¹  Aquino, Thiago M. de¹  Tenório, Rômulo P.¹  Alves, Antônio J.¹  Faria, Antônio R. de¹  Lima, José G. de¹  Góes, Alexandre J. S.¹ 

关键词: thiosemicarbazone;    preparation methods;    synthetic applications.;   

DOI  :  10.1590/S0100-40422005000600018

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Thiosemicarbazones are a class of compounds known by their chemical and biological properties, such as antitumor, antibacterial, antiviral and antiprotozoal activity. Their ability to form chelates with metals has great importance in their biological activities. Their synthesis is very simple, versatile and clean, usually giving high yields. They are largely employed as intermediates, in the synthesis of others compounds. This article is a survey of some of these characteristics showing their great importance to organic and medicinal chemistry.

【 授权许可】

Unknown