Validation for chromatographic and electrophoretic methods

Química Nova

Instituto de Tecnologia do Paraná, Curitiba¹  Ribani, Marcelo¹  Jardim, Isabel Cristina Sales Fontes¹  Melo, Lúcio Flávio Costa¹  Collins, Carol H.¹  Bottoli, Carla Beatriz Grespan¹  Universidade Estadual de Campinas, Campinas¹ 

关键词: validation;    legislation;    separation methods.;   

DOI  :  10.1590/S0100-40422004000500017

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

The validation of an analytical method is fundamental to implementing a quality control system in any analytical laboratory. As the separation techniques, GC, HPLC and CE, are often the principal tools used in such determinations, procedure validation is a necessity. The objective of this review is to describe the main aspects of validation in chromatographic and electrophoretic analysis, showing, in a general way, the similarities and differences between the guidelines established by the different Brazilian and international regulatory agencies.

【 授权许可】

Unknown