Chemical contituents of Alchornea glandulosa (Euphorbiaceae)

Química Nova

Foglio, Mary Ann¹  Centro Pluridisciplinar de Pesquisas Químicas, Biológicas e Agrícolas, Campinas¹  Nakamura, Celso Vataru¹  Nazari, Anelise Samara¹  Conegero, Leila de Souza¹  Carvalho, João Ernesto de¹  Ide, Regina Massae¹  Dias Filho, Benedito Prado¹  Sarragiotto, Maria Helena¹  Universidade Estadual de Maringá, Maringá¹ 

关键词: Alchornea glandulosa;    chemical constituents;    antimicrobial and antiproliferative assays.;   

DOI  :  10.1590/S0100-40422003000600008

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Chemical investigation of the leaves of Alchornea glandulosa (Euphorbiaceae) afforded a mixture of b-sitosterol and stigmasterol, the terpenoid loliolide, the guanidine alkaloid N-1,N-2,N-3-triisopentenylguanidine and the phenolic compound corilagin. The structures of these compounds were elucidated by spectroscopic analysis. The antimicrobial and antiproliferative properties of the crude methanolic extract of the leaves and of fractions from its fractionation, were investigated against a series of bacteria and fungi, as well as against four human cancer cell lines.

【 授权许可】

Unknown