Chemical contituents of Alchornea glandulosa (Euphorbiaceae)

Quimica nova

Foglio, Mary Ann¹  Carvalho, João Ernesto de¹  Nakamura, Celso Vataru²  Nazari, Anelise Samara²  Conegero, Leila de Souza²  Ide, Regina Massae²  Dias Filho, Benedito Prado²  Sarragiotto, Maria Helena² 

[1] Centro Pluridisciplinar de Pesquisas Químicas, Biológicas e Agrícolas, Campinas;Universidade Estadual de Maringá, Maringá

关键词: Alchornea glandulosa;    chemical constituents;    antimicrobial and antiproliferative assays.;   

DOI  :  10.1590/S0100-40422003000600008

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

Chemical investigation of the leaves of Alchorneaglandulosa (Euphorbiaceae) afforded a mixture of b-sitosterol and stigmasterol,the terpenoid loliolide, the guanidine alkaloid N-1,N-2,N-3-triisopentenylguanidineand the phenolic compound corilagin. The structures of these compounds wereelucidated by spectroscopic analysis. The antimicrobial and antiproliferativeproperties of the crude methanolic extract of the leaves and of fractions fromits fractionation, were investigated against a series of bacteria and fungi,as well as against four human cancer cell lines.

【 授权许可】

CC BY