Synthesis of analgesics paracetamol and phenacetin and the sweetener dulcin: a project for undergraduate organic chemistry laboratory

Química Nova

Baptistella, Lúcia H. B.¹  Imamura, Paulo M.¹  Giacomini, Rosana A.¹  Universidade Estadual de Campinas, Campinas¹ 

关键词: aromatic compounds;    analgesics paracetamol and phenacetin;    sweetener dulcin.;   

DOI  :  10.1590/S0100-40422003000200024

学科分类：化学（综合）

来源: Sociedade Brasileira de Quimica

【 摘 要 】

A synthesis of artificial sweetener dulcin starting from nitrobenzene was elaborated for undergraduate organic laboratory course. Paracetamol and phenacetin, both physiologically active analgesic compounds, were also prepared as intermediates. Besides a large scope of discussion subjects related with organic synthesis, interesting lectures about analgesics and sweeteners may also be performed in this project. The advantage of this project is the adaptability according to the conditions offered by the course, i.e., convenience and/or availability of time and reagents.

【 授权许可】

Unknown